B.K.N. Muthugobal1, G. Ramesh2, S. Parthasarathy3* S. Suvaithenamudhan4 and K. Muthuvel Prasath3
1Department of Mathematics, Tamilavel Umamaheswaranar Karanthai Arts College, Karanthai, Thanjavur 613 002, Tamil Nadu, India
2Ramanujan Research Centre, Department of Mathematics, Government Arts College (Autonomous), Kumbakonam 612 001, Tamil Nadu, India
3Department of Bioinformatics, School of Life Sciences, Bharathidasan University, Tiruchirappalli 620 024, Tamil Nadu, India
4Department of Biotechnology and Bioinformatics, Bishop Heber College (Autonomous), Tiruchirappalli 620 017, Tamil Nadu, India
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The entire set of proteins can be considered as the union of three subsets namely the i) ‘Born’ (or) Natural proteins denoted by A, ii) ‘Never Born Proteins (NBPs)’ denoted as B and iii) ‘Cannot be Born’ (or) Impossible proteins denoted by C as given in Figure [Source: Muthugopal et al., BioSystems, 198 (2020) 104280]. The "GenNBPSeq" is an online web server  to generate a Never Born Protein (NBP) sequence and its corresponding DNA sequence, using the Partitioned Gray code representations of Universal Genetic Code combined with a novel Toeplitz matrix approach, as outlined in Muthugobal et. al. (2020). We generate the three sample NBP sequences NBP_SEQ_1, NBP_SEQ_2 and NBP_SEQ_3 using this "GenNBPSeq" online web server.
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