Generate Never Born Protein Sequences
B.K.N. Muthugobal1, G. Ramesh2, K. Muthuvel Prasath3, S. Suvaithenamudhan3 and S. Parthasarathy3*
1Department of Mathematics, Bharathidasan University Constitutent Arts & Science College, Nannilam, Thiruvarur 610 105, Tamil Nadu, India
2Ramanujan Research Centre, Department of Mathematics, Government Arts College (Autonomous), Kumbakonam 612 001, Tamil Nadu, India
3Department of Bioinformatics, School of Life Sciences, Bharathidasan University, Tiruchirappalli 620 024, Tamil Nadu, India
* For all correspondence


         The "GenNBPSeq" is an online web server to generate a Never Born Protein (NBP) sequence and its corresponding DNA sequence, using the Partitioned Gray code representations of Universal Genetic Code combined with a novel Toeplitz matrix approach, as outlined in Muthugobal et. al. (2019)[1]. We generate the three sample NBP sequences NBP_SEQ_1, NBP_SEQ_2 and NBP_SEQ_3 using this "GenNBPSeq" online web server.

Choose Toeplitz Matrix Order

Click here for a brief Description of Generation of the three Sample NBP Sequences.

Click here to get Sample Input and Output NBP_SEQ_1, NBP_SEQ_2 and NBP_SEQ_3.

Click here to get Partitioned Toeplitz Matrix types PTM1, PTM2, PTM3 and PTM4.

Click here for Supplementary data.

Click here for Universal Genetic Code.

Please Cite
[1] B.K.N. Muthugobal, G. Ramesh, K. Muthuvel Prasath, S. Suvaithenamudhan and S. Parthasarathy*(2019) Gray Code Representation of the Universal Genetic Code and Generation of Never Born Protein Sequences using Toeplitz Matrix Approach: Sequence and Structure Analysis. To be communicated.

Further Reference
He M, Petoukhov S and Ricci PE (2004) Genetic code, Hamming distance, and stochastic matrices. Bulletin of Mathematical Biology, 66, 965-973.

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© 2018 - S. Parthasarathy, Bharathidasan University, India