PredictSuperFam - PB

(Applicable for Twilight Zone Protein Sequences)

Developed by K. Muthuvel Prasath1, V. Suresh2, K. Ganesan1 and S. Parthasarathy1*
1Dept. of Bioinformatics,School of Life Sciences, Bharathidasan University, Tiruchirappalli 620 024, India
2Department of Paediatrics, Emory University School of Medicine & Children’s Healthcare of Atlanta, GA, USA
* For correspondence


The PredictSuperFam-PB is a superfamily recognition server based on Protein Blocks. The protein Blocks are one of the Structural Alphabets used to describe regions of the protein backbone. Here, we present a protein superfamily recognition method based on Protein Blocks for the annotation of twilight zone sequences.

In our method, we align the predicted Protein Blocks of a query amino acid sequence with a library of assigned Protein Blocks of 1654 known superfamily representatives using the local pair-wise alignment.